Middlesbrough - Chelsea 3-0
Date: February 11, 2006
Tournament: Premier league

The leader of the Premier League was defeated for the first time since November 2005 . Middlesbrough lost Aston Villa 0:4 a week earlier so nobody had expected such a score. The first goal Mourinho team missed at the 78th second of the match. After the game Jose said: 

"We lost to Man City and didn’t deserve it, we lost to Manchester United and didn’t deserve it. Today we lost 0-3 and we deserved it." 

In a couple of months he led Chelsea to the next championship.

Barcelona - Real 5:0
Date: November 29, 2010
Tournament: La Liga

This was the biggest defeat in Mourinho's career at the time. The first El Clásico turned into a catastrophe for Jose Mourinho. All that Real players could do in that match was to break the rules. All in all the judge showed 14 yellow cards and Sergio Ramos was sent off. 

"It's not a shame, but I'm very upset."

Borussia - Real - 4: 1
Date: April 24, 2013
Tournament: Champions League

Jose Mourinho is used to the fact that his team had only one opponent - Barcelona. After the Catalans lost the match to Munich (0:4) Real started the game with Dortmund with the expression of the winners on their faces. The team struggled only the first 45 minutes. Robert Lewandowski's hat trick discouraged everyone in the second half (he also scored the first goal). And first of all Mourinho. 

«I don’t understand how 1:1 turned into 4:1. Everything happened so quickly. " 

This was the biggest defeat of Jose in 106 matches of the Champions League.

Chelsea - Manchester United - 4:0
Date: October 23, 2016
Tournament: Premier League

Jose returned to Stamford Bridge for the first time since he was fired from Chelsea. However Pedro's goal at the first minute disappointed him. It was the second time in the history of the Premier League when Mourinho’s team missed four goals.

Manchester - Tottenham 0: 3
Date: August 27, 2018
Tournament: Premier League

Mourinho received the biggest home defeat in his career. But despite the fact he said that his team deserved praise from fans. He also urged journalists to treat him with respect. 

The score is 3-0, but I also won three champion titles in Premier League. I won more championships than the other 19 coaches all together. I have three titles, they have - 2. Bestow your respect